Compatibility Results in Seconds, Not Hours
VIRTUAL CROSSMATCH IS ONLY AS USEFUL AS HOW FAST THE RESULTS REACH THE SURGEON
Faster Crossmatch Results for Better Transplant Decisions
A Human Leukocyte Antigen (HLA) Virtual Crossmatch assesses rejection risk by comparing a recipient's antibody profile with a donor's HLA antigens. Most programs already perform this step. The challenge is getting the result into the offer evaluation workflow fast enough to support decision-making.
When crossmatch operates as a separate process, coordinators must initiate, track, and wait for results while offer evaluations continue. The result can be added cold ischemic time, increased workload, and decisions made without complete information.
Every minute crossmatch adds to the evaluation window is a minute of cold ischemic time. The clinical and operational cost compounds with every offer your program handles.
High-Resolution Data, Real-Time Compatibility Insights
Powered by Afflo's high-resolution data platform, Buckeye's Automated Virtual Crossmatch compares donor and recipient profiles automatically. It accepts HLA typing at both low and high resolution, processes antibody files without manual re-entry, and delivers results in seconds. The output appears as a standardized crossmatch report within the LENS offer presentation, so compatibility data is organized and available when the offer is presented to the surgeon.
When confirmatory hard crossmatches are required, the system coordinates directly with HLA labs, preserving flexibility for each center's protocols without delaying offer evaluation.
High-resolution HLA Matching
Allele-specific results with automated DQ/DP handling and untested allele detection. Fewer false positives, fewer unnecessary declines.
Eplet-level Analysis
Deep antibody profiling gives teams confidence in every acceptance decision, not just a flag to investigate further.
Multiple Candidates at Once
Parallel review of multiple recipients eliminates sequential evaluation delays during time-sensitive or high-volume cases.
Integrated into Offer Evaluation
Results surface inside LENS with the offer — not as a separate step to initiate, track, and wait for before the surgeon is called.
Faster Crossmatch Improves Acceptance Rates, Cold Time and SRTR Outcomes
Higher-resolution data reduces false positives, resulting in fewer organs being declined that could have been accepted. Faster results shorten the evaluation window, reducing cold ischemic time and supporting better graft survival outcomes, along with stronger SRTR observed-to-expected performance.
For programs participating in the mandatory IOTA model, these outcomes directly influence performance scores. Offer acceptance efficiency and graft survival are two of the highest-leverage domains. Automated VxM helps improve both, without adding staff burden or requiring after-hours lab work.
How Much Time is Crossmatch Adding to Your Offer Evaluation Window?
Discover how Buckeye’s Automated Virtual Crossmatch helps you streamline compatibility assessments and strengthen transplant outcomes.